ES8L2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityES8L2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: ES8L2 antibody detects endogenous levels of ES8L2. Description: EPS8L2 Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. Belongs to the EPS8 family. Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin. 2 isoforms of the human protein are produced by alternative splicing.Function: Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. In the cochlea, is required for stereocilia maintenance in adult hair cells (By similarity).Subunit Structure: Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates wi
ImmunogenImmunogen: A synthesized peptide derived from human ES8L2 Subcellular Location: Cytoplasm. Tissue Specificity: Detected in fibroblasts and placenta. Predicted Cross Reactivity: Zebrafish, Bovine, Horse, Dog, Chicken, Xenopus Similarity: Zebrafish (100%), Bovine (100%), Horse (100%), Dog (100%), Chicken (91%), Xenopus (100%)
Other Names[Epidermal growth factor receptor kinase substrate 8 like protein 2; Epidermal growth factor receptor kinase substrate 8-like protein 2; Epidermal growth factor receptor pathway substrate 8 like protein 2; Epidermal growth factor receptor pathway substrate 8 related protein 2; Epidermal growth factor receptor pathway substrate 8-related protein 2; EPS8 like 2; EPS8 like protein 2; EPS8 related protein 2; EPS8-like protein 2; EPS8-related protein 2; EPS8L 2; EPS8L2; EPS8R 2; EPS8R2; ES8L2_HUMAN; FLJ16738; FLJ21935; FLJ22171; MGC126530; MGC3088]
Gene, Accession #[ES8L2], Gene ID: 64787, NCBI: NP_073609.2, UniProt: Q9H6S3
Catalog #MBS9600358
Price$240, $280
Order / More InfoES8L2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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