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Antigenic Specificity | ES8L2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ES8L2 antibody detects endogenous levels of ES8L2. Description: EPS8L2 Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. Belongs to the EPS8 family. Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin. 2 isoforms of the human protein are produced by alternative splicing.Function: Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. In the cochlea, is required for stereocilia maintenance in adult hair cells (By similarity).Subunit Structure: Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates wi |
Immunogen | Immunogen: A synthesized peptide derived from human ES8L2 Subcellular Location: Cytoplasm. Tissue Specificity: Detected in fibroblasts and placenta. Predicted Cross Reactivity: Zebrafish, Bovine, Horse, Dog, Chicken, Xenopus Similarity: Zebrafish (100%), Bovine (100%), Horse (100%), Dog (100%), Chicken (91%), Xenopus (100%) |
Other Names | [Epidermal growth factor receptor kinase substrate 8 like protein 2; Epidermal growth factor receptor kinase substrate 8-like protein 2; Epidermal growth factor receptor pathway substrate 8 like protein 2; Epidermal growth factor receptor pathway substrate 8 related protein 2; Epidermal growth factor receptor pathway substrate 8-related protein 2; EPS8 like 2; EPS8 like protein 2; EPS8 related protein 2; EPS8-like protein 2; EPS8-related protein 2; EPS8L 2; EPS8L2; EPS8R 2; EPS8R2; ES8L2_HUMAN; FLJ16738; FLJ21935; FLJ22171; MGC126530; MGC3088] |
Gene, Accession # | [ES8L2], Gene ID: 64787, NCBI: NP_073609.2, UniProt: Q9H6S3 |
Catalog # | MBS9600358 |
Price | $240, $280 |
Order / More Info | ES8L2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |