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Antigenic Specificity | Phospho-Ser234 Beclin-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Specific for the ~60k beclin1 protein phosphorylated at Ser234. Immunolabeling of the beclin-1 band is decreased in the beclin-1 alanine substitution mutant. Additional bands may be observed in non-immunoprecipitated lysates. Affinity purified rabbit polyclonal antibody |
Immunogen | Antigen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser234 of human beclin-1. Immunogen Information: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser234 conjugated to KLH. Immunogen Species: Human |
Other Names | [beclin-1; Beclin-1; beclin-1; ATG6 autophagy related 6 homolog; coiled-coil myosin-like BCL2-interacting protein; beclin 1 (coiled-coil, moesin-like BCL2 interacting protein); beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1, autophagy related; Coiled-coil myosin-like BCL2-interacting protein; Protein GT197], [BECN1; BECN1; ATG6; VPS30; beclin1; GT197] |
Gene, Accession # | [BECN1], Gene ID: 8678, NCBI: NP_003757.1, UniProt: Q14457 |
Catalog # | MBS502210 |
Price | $360 |
Order / More Info | Phospho-Ser234 Beclin-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | • Liang, XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H, Levine B. (1999) Induction of autophagy and inhibition of tumorigenesis by beclin-1. Nature 402(6762):672-676.• Richard C. Wang, Yongjie Wei, Zhenyi An, Zhongju Zou, Guanghua Xiao, Govind Bhagat, Michael White, Julia Reichelt, and Beth Levine (2012) Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation. Science 338:956-959. |