SEPT2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySEPT2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: SEPT2 antibody detects endogenous levels of total 41519. Function: Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830). Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localizat
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Cytoplasm. Cytoplasm; Cytoskeleton. Cytoplasm; Cytoskeleton; Spindle. Chromosome; Centromere; Kinetochore. Cleavage Furrow. Midbody. Cytoplasm; Cell Cortex. Cell Projection; Cilium Membrane. Tissue Specificity: Widely expressed. Up-regulated in liver cancer. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (92%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit
Other Names[DIFF6; hNEDD5; KIAA0158; NEDD 5; NEDD5; Neural precursor cell expressed developmentally down regulated 5; Neural precursor cell expressed developmentally down regulated protein 5; Pnutl3; Protein NEDD5; SEPT2; septin 2]
Gene, Accession #[SEPT2], Gene ID: 4735, NCBI: NP_001008491.1, UniProt: Q15019
Catalog #MBS9605912
Price$240, $280
Order / More InfoSEPT2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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