Edit |   |
Antigenic Specificity | SEPT2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SEPT2 antibody detects endogenous levels of total 41519. Function: Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830). Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localizat |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm. Cytoplasm; Cytoskeleton. Cytoplasm; Cytoskeleton; Spindle. Chromosome; Centromere; Kinetochore. Cleavage Furrow. Midbody. Cytoplasm; Cell Cortex. Cell Projection; Cilium Membrane. Tissue Specificity: Widely expressed. Up-regulated in liver cancer. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (92%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit |
Other Names | [DIFF6; hNEDD5; KIAA0158; NEDD 5; NEDD5; Neural precursor cell expressed developmentally down regulated 5; Neural precursor cell expressed developmentally down regulated protein 5; Pnutl3; Protein NEDD5; SEPT2; septin 2] |
Gene, Accession # | [SEPT2], Gene ID: 4735, NCBI: NP_001008491.1, UniProt: Q15019 |
Catalog # | MBS9605912 |
Price | $240, $280 |
Order / More Info | SEPT2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |