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Antigenic Specificity | SERPINA3 |
Clone | [112] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | Protein A purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a member of the serine protease inhibitor class, and is a plasma alpha globulin glycoprotein which increases in the blood during the inflammatory process. SerpinA3, is also an inhibitor of neutrophil cathepsin G, mast cell chymases and pancreatic chymotrypsin. SerpinA3 is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease. SerpinA3 has also been implicated in the pathology of a number of devastating human diseases including chronic obstructive pulmonary disease (COPD), Parkinson's disease (PD), Alzheimer's disease (AD), Stroke, Cystic Fibrosis, Cerebral Haemorrhage and Multiple |
Immunogen | Immunogen: Fusion protein of alpha 1 Antichymotrypsin / AACT |
Other Names | [SERPINA3; AACT; AACT; ACT; Alpha-1-antichymotrypsin His-Pro-less; Antichymotrypsin; Cell growth inhibiting gene 24/25 protein; Cell growth-inhibiting gene 24/25 protein; GIG24; GIG25; Growth inhibiting protein 24; Growth inhibiting protein 25; MGC88254; Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase; antitrypsin) member 3; Serine (or cysteine) proteinase inhibitor clade A member 3; Serine proteinase inhibitor clade A member 3; Serpin A3; Serpin family A member 3; Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3; SERPINA3; A1 Antichymotrypsin; Alpha 1 antichymotrypsin] |
Gene, Accession # | [SERPINA3], Gene ID: 12, NCBI: NP_001076.2, UniProt: P01011 |
Catalog # | MBS2541808 |
Price | $220, $290, $435 |
Order / More Info | SERPINA3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |