Human MCAM Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman MCAM
Clone[4H55]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Flow Cytometry (FC/FACS)
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DescriptionMelanoma Cell Adhesion Molecule (MCAM)/CD146 is a surface antigen on metastatic human melanoma cells originally called MUC18 or A32. The 113 kDa glycoprotein is a member of the immunoglobulin superfamily that shows significant homology to several cell adhesion molecules, notably N-CAM. MCAM/CD146 is also identical to the endothelial cell antigen S-Endo. In addition to melanoma and endothelial cells, MCAM/CD146 is expressed on smooth muscle cells, cerebellar cortex, trophoblasts and activated T cells. MCAM/CD146 is also expressed on a variety of malignant cell types including: vascular and smooth muscle tumors gliomas and neuroblastomas, prostate tumors, and in tumors arising from hematologic malignancies. As a proposed adhesion receptor, MC
ImmunogenAntibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with extracellular domain of human recombinant protein of MCAM (also called CD146).
Other Names[MCAM; CD146; MUC18], [MCAM; MCAM; CD146; MUC18; MUC18]
Gene, Accession #[MCAM], Gene ID: 4162, NCBI: NP_006491.2, UniProt: P43121
Catalog #MBS690159
Price$490
Order / More InfoHuman MCAM Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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