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Antigenic Specificity | Mouse Sik2 (Center), 606-633 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.35 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Sik2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 606-633 amino acids from the Central region of mouse Sik2. Phosphorylates 'Ser-789' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators. |
Immunogen | n/a |
Other Names | [Serine/threonine-protein kinase SIK2; Salt-inducible kinase 2; SIK-2; Serine/threonine-protein kinase SNF1-like kinase 2; Sik2; Snf1lk2] |
Gene, Accession # | [Sik2], Gene ID: 235344, NCBI: NP_848825.2, UniProt: Q8CFH6 |
Catalog # | MBS9211560 |
Price | $165, $370 |
Order / More Info | Mouse Sik2 (Center), 606-633 Antibody from MYBIOSOURCE INC. |
Product Specific References | Trivedi, C.M., et al. Dev. Cell 19(3):450-459(2010) Muraoka, M., et al. Am. J. Physiol. Endocrinol. Metab. 296 (6), E1430-E1439 (2009) : Du, J., et al. Obesity (Silver Spring) 16(3):531-538(2008) Katoh, Y., et al. FEBS J. 273(12):2730-2748(2006) Horike, N., et al. J. Biol. Chem. 278(20):18440-18447(2003) |