Edit |   |
---|---|
Antigenic Specificity | Mucin-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total Mucin-1 polyclonal antibody. The alpha subunit has cell adhesive properties.Can act both as an adhesion and an anti-adhesion protein.May provide a protective layer on epithelial cells against bacterial and enzyme attack. Ref.26 Ref.37 Ref.40 Ref.45 Ref.46 Ref.49 Ref.52 Ref.53 Ref.56. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway.Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response.Binds, together wi |
Immunogen | n/a |
Other Names | [PUM; MUC1; Breast carcinoma-associated antigen DF3 Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associa] |
Gene, Accession # | Gene ID: 4582, NCBI: NP_001018016.1, UniProt: P15941 |
Catalog # | MBS9415931 |
Price | $320 |
Order / More Info | Mucin-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |