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Antigenic Specificity | ST5 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ST5 |
Other Names | [suppression of tumorigenicity 5 protein isoform 1; Suppression of tumorigenicity 5 protein; suppression of tumorigenicity 5 protein; suppression of tumorigenicity 5; DENN domain-containing protein 2B; HeLa tumor suppression 1] |
Gene, Accession # | [ST5], Gene ID: 6764, NCBI: NP_005409.3, UniProt: P78524 |
Catalog # | MBS3221480 |
Price | $335 |
Order / More Info | ST5 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |