Apaf-1 [5E11] Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Apaf-1 [5E11] |
| Clone | [5E11] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Apaf-1 Monoclonal Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. The mammalian homologous of the key cell death gene CED-4 in C. elegans was identified recently from human and mouse and designated Apaf1 for apoptosis protease-activating factor 1. Apaf1 binds to cytochrome c (Apaf2) and caspase-9 (Apaf3), which leads to caspase-9 activation. Activated caspase-9 in turn cleaves and activates caspase-3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. Apaf1 can also associate with caspas |
| Immunogen | Immunogen: A peptide corresponding to amino acids near the carboxy terminus of human Apaf1. Buffer: Apaf-1 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [Apaf-1 [5E11] : CED4; APAF-1; apoptotic peptidase activating factor 1], [APAF1; APAF1; CED4; APAF-1; KIAA0413; APAF-1] |
| Gene, Accession # | [APAF1], Gene ID: 317, NCBI: AAC51678, UniProt: O14727 |
| Catalog # | MBS150007 |
| Price | $375 |
| Order / More Info | Apaf-1 [5E11] Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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