Edit |   |
---|---|
Antigenic Specificity | SHEEP CD14 |
Clone | [VPM65] |
Host Species | Mouse |
Reactive Species | sheep |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) Formalin, ELISA (EIA), Flow Cytometry (FC/FACS), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse Anti Sheep CD14 antibody, clone VPM65 recognizes Ovine CD14, a GPI-anchored 55 kDa membrane glycoprotein and monocyte/macrophage differentiation antigen belonging to the lipopolysaccharide receptor family. Ovine CD14 is expressed by monocytes, macrophages and peripheral blood granulocytes. CD14 acts as a receptor for the potent bacterial endotoxin, lipopolysaccharide (LPS), facilitated by LPS-binding protein (LBP). The binding of LPS to CD14 results in cell activation, the release of cytokines and the inflammatory response, which has been shown to upregulate the cell surface expression of adhesion molecules. |
Immunogen | n/a |
Other Names | [CD14; Monocyte differentiation antigen CD14; monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; CD_antigen: CD14], [CD14; CD14] |
Gene, Accession # | [CD14], Gene ID: 281048, NCBI: BAA21517.1 |
Catalog # | MBS224774 |
Price | $320 |
Order / More Info | SHEEP CD14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |