LRRK2/Dardarin Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | LRRK2/Dardarin |
| Clone | [S138-6] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | APC-Cy7 conjugate |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects >200 kDa. LRRK2 is a large protein with multiple domains including several ankyrin, leucine-rich, and WD40 repeats, a Ras-like small GTPase family domain named Roc, and a kinase domain that is closely related to the RIP kinase domain. LRRK2 gene is expressed in brain as well as in other tissues such as lung, liver and heart. LRRK2 might be central to the pathogenesis of several major neurodegenerative diseases associated with parkinsonism. Several dominantly inherited missense mutations in the gene encoding LRRK2 have been identified in several families that exhibit a broad spectrum of neuropathological features. |
| Immunogen | Immunogen: Fusion protein, amino acids 1-500 (N-terminus) of human LRRK2. 83% identical in mouse and rat. No significant identity with LRRK1. |
| Other Names | [Mouse Human LRRK2/Dardarin IgG1; LRRK2/Dardarin : APC/Cy7; Leucine-rich repeat kinase 2; RIP7; PARK8; Dardarin; ROCO 2; RIPK7; Leucine-rich repeat serine/threonine-protein kinase 2; augmented in rheumatoid arthritis 17] |
| Gene, Accession # | [LRRK2], Gene ID: 120892, NCBI: NP_940980.3, UniProt: Q5S007 |
| Catalog # | MBS8003370 |
| Price | $510 |
| Order / More Info | LRRK2/Dardarin Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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