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Antigenic Specificity | NOXA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NOXA Antibody detects endogenous levels of NOXA. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.Similarity: The BH3 motif is essential for pro-apoptotic activity.Belongs to the PMAIP1 family. |
Immunogen | Immunogen: A synthesized peptide derived from human NOXA. Fragment: Fab fragment |
Other Names | [NOXA - N-terminal; Adult T cell leukemia derived PMA responsive; APR; APR_HUMAN; ATL-derived; Immediate early response protein APR; Immediate-early-response protein APR; NOXA; Phorbol 12 myristate 13 acetate induced protein 1; Phorbol-12-myristate-13-acetate-induced protein 1; PMA induced protein 1; PMA-induced protein 1; PMA-responsive gene; Pmaip1; Protein Noxa;] |
Gene, Accession # | [NOXA], Gene ID: 5366, NCBI: NP_066950.1, UniProt: Q13794 |
Catalog # | MBS9611943 |
Price | $240, $280 |
Order / More Info | NOXA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |