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Antigenic Specificity | PRKCE |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total PRKCE protein. Activation of protein kinase C (PKC) is one of the earliest events in a cascade that controls a variety of cellular responses, including secretion, gene expression, proliferation, and muscle contraction (1,2). PKC isoforms belong to three groups based on calcium dependency and activators. Classical PKCs are calcium-dependent via their C2 domains and are activated by phosphatidylserine (PS), diacylglycerol (DAG), and phorbol esters (TPA, PMA) through their cysteine-rich C1 domains. Both novel and atypical PKCs are calcium-independent, but only novel PKCs are activated by PS, DAG, and phorbol esters (3-5). Members of these three PKC groups contain a pseudo-substrate or autoinhibito |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human PRKCE. |
Other Names | [MGC125656; MGC125657; PKCE; nPKC-epsilon] |
Gene, Accession # | [PRKCE], Gene ID: 5581, NCBI: NP_005391.1, UniProt: Q02156 |
Catalog # | MBS9412046 |
Price | $255 |
Order / More Info | PRKCE Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |