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Antigenic Specificity | TESC - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, yeast |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against TESC. It was validated on Western BlotTarget Description: TESC functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. It promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane and promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. It is essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. It is also involved in granulocytic differentiation in a ERK-dependent manner and inhibits the phosphatase activity of calcineurin. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TESC |
Other Names | [calcineurin B homologous protein 3 isoform 1; Calcineurin B homologous protein 3; calcineurin B homologous protein 3; tescalcin; Tescalcin; TSC] |
Gene, Accession # | [TESC], Gene ID: 54997, NCBI: NP_060369, UniProt: Q96BS2 |
Catalog # | MBS3213153 |
Price | $335 |
Order / More Info | TESC - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |