Bax (Center), 69-98 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBax (Center), 69-98
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: mouse, rat)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.28
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis Bax antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the Central region of human Bax. The protein encoded by this gene belongs to the BCL2protein family. BCL2 family members form hetero- or homodimers andact as anti- or pro-apoptotic regulators that are involved in awide variety of cellular activities. This protein forms aheterodimer with BCL2, and functions as an apoptotic activator.This protein is reported to interact with, and increase the openingof, the mitochondrial voltage-dependent anion channel (VDAC), whichleads to the loss in membrane potential and the release ofcytochrome c. The expression of this gene is regulated by the tumor
Immunogenn/a
Other Names[Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BAX; BCL2L4]
Gene, Accession #[BAX], Gene ID: 581, NCBI: NP_004315.1, UniProt: Q07812
Catalog #MBS9214479
Price$165, $370
Order / More InfoBax (Center), 69-98 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesBailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Montessuit, S., et al. Cell 142(6):889-901(2010) Ding, J., et al. J. Biol. Chem. 285(37):28749-28763(2010) Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press : Yu, D.K., et al. Zhonghua Zhong Liu Za Zhi 32(5):324-327(2010)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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