Human Histone-lysine N-methyltransferase EZH1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Histone-lysine N-methyltransferase EZH1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. |
| Immunogen | Immunogen: Recombinant human Histone-lysine N-methyltransferase EZH1 protein (160-280aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-20347 / sc-20349 / sc-292275 |
| Other Names | [ENX-2; Enhancer of zeste homolog 1; EZH1; KIAA0388], [EZH1; EZH1; KMT6B; KIAA0388] |
| Gene, Accession # | [EZH1], Gene ID: 2145, NCBI: NP_001982.2, UniProt: Q92800 |
| Catalog # | MBS968984 |
| Price | $120, $160 |
| Order / More Info | Human Histone-lysine N-methyltransferase EZH1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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