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Antigenic Specificity | ST |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ST antibody detects endogenous levels of total ST. Function: Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.Subunit Structure: Monomer or homooligomer (By similarity). Interacts with TGFB1I1. Interacts (via sialylated form) with MYH9. Interacts with SEC23A, SEC24C and PATJ. Interacts with NOS1; the interaction may diminish the cell surfac |
Immunogen | Immunogen: A synthesized peptide derived from human ST Subcellular Location: Cell Membrane. Endomembrane System. Endosome membrane. Translocates from intracellular locations to the plasma membrane. Density of transporter molecules on the plasma membrane is itself regulated by serotonin. Tissue Specificity: Expressed in platelets (at protein level). Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Dog, Chicken Similarity: Pig (100%), Bovine (92%), Horse (100%), Sheep (92%), Dog (92%), Chick |
Other Names | [5 HTT; 5 HTTLPR; 5 hydroxytryptamine (serotonin) transporter; 5 hydroxytryptamine transporter; 5HT transporter; 5HTT; hSERT; HTT; Na+/Cl-dependent serotonin transporter; OCD1; SC6A4_HUMAN; Serotonin transporter 1; SERT; SERT1; Slc6a4; Sodium dependent serotonin transporter; Sodium-dependent serotonin transporter; Solute carrier family 6 (neurotransmitter transporter) member 4; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; Solute carrier family 6 member 4] |
Gene, Accession # | [ST], Gene ID: 6532, NCBI: NP_001036.1, UniProt: P31645 |
Catalog # | MBS9608933 |
Price | $240, $280 |
Order / More Info | ST Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |