GS28 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | GS28 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: GS28 antibody detects endogenous levels of total GS28. Function: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.S |
| Immunogen | Immunogen: A synthesized peptide derived from human GS28 Subcellular Location: Cell Membrane, Endoplasmic Reticulum and Golgi Apparatus Tissue Specificity: Expression induced by hydrogen peroxide in neuronal cells. By monocrotaline in pulmonary epithelial cells (at protein level). Negatively regulated by OSBPL7 via GABARAPL2 leading to degradation on proteasomes (at protein level). Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (10 |
| Other Names | [28 kDa cis Golgi SNARE p28; 28 kDa Golgi SNARE protein; cis-golgi SNARE; golgi integral membrane protein 2; Golgi SNAP receptor complex member 1; Golgi SNARE 28 kDa; GOLIM2; GOS28; GOS28/P28; GOSR1; GS25; Gs28; P28] |
| Gene, Accession # | [GS28], Gene ID: 9527, NCBI: NP_001007025.1, UniProt: O95249 |
| Catalog # | MBS9602125 |
| Price | $240, $280 |
| Order / More Info | GS28 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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