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Antigenic Specificity | MVP |
Clone | [8B12] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Mouse IgG monoclonal antibody for MVP detection. Tested with WB, IHC-P, FCM in Human; Mouse; Rat.Background: Major vault protein is a protein that in humans is encoded by the MVP gene. This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively s |
Immunogen | Immunogen: E. coli-derived human MVP recombinant protein (Position: A2-H259). |
Other Names | [Major vault protein; MVP; Lung resistance-related protein; MVP; LRP] |
Gene, Accession # | [MVP], Gene ID: 9961, NCBI: NP_005106.2, UniProt: Q14764 |
Catalog # | MBS1752894 |
Price | $315 |
Order / More Info | MVP Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: MVP major vault protein. 2. Izquierdo MA, Scheffer GL, Flens MJ, Schroeijers AB, van der Valk P, Scheper RJ (Jun 1996). Major vault protein LRP-related multidrug resistance. European Journal of Cancer. 32A (6): 979-84. |