Edit |   |
---|---|
Antigenic Specificity | BCAT1 |
Clone | [AT3C8] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, k |
Format | Protein A purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1 mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BCAT1, also known as branched chain amino-acid transaminase (cytosolic form), catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. BCAT1 is expressed in the brain and kidney. Overexpressed in MYC-induced tumors such as Burkitt's lymphoma. |
Immunogen | Immunogen: Recombinant human BCAT1 (1-386aa) purified from E. coli |
Other Names | [Branched chain amino-acid transaminase cytosolic; Branched chain amino-acid transaminase; cytosolic; BCATC; BCT1; ECA39; MECA39; PNAS121; PP18], [BCAT1; BCAT1; BCT1; PP18; BCATC; ECA39; MECA39; PNAS121; BCT1; ECA39; BCAT(c)] |
Gene, Accession # | [BCAT1], Gene ID: 586, NCBI: NP_005495, UniProt: P54687 |
Catalog # | MBS200348 |
Price | $240, $315 |
Order / More Info | BCAT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Goto M., et al. (2005) J Biol Chem. 280: 37246-37256.; Schuldiner O., et al. (1996) Proc Natl Acad Sci USA. 93: 7143-7148. |