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Antigenic Specificity | Phospho-c-PLA2 (Ser505) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human,mouse,rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-c-PLA2 (Ser505) Antibody detects endogenous levels of c-PLA2 only when phosphorylated at Serine 505. cPLA2 a calcium-dependent phospholipase A2 that catalyzes the release of arachidonic acid from membrane phospholipids. Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. |
Immunogen | Immunogen: A synthesized peptide derived from human c-PLA2 around the phosphorylation site of Serine 505. Subcellular Location: Cytosol;Endoplasmic reticulum;Golgi apparatus;Mitochondrion;. Tissue Specificity: Expressed in various tissues such as macrophages, platelets, neutrophils, fibroblasts and lung endothelium. Similarity: The N-terminal C2 domain associates with lipid membranes upon calcium binding. It modulates enzyme activity by presenting the active site to its substrate in response to |
Other Names | [cytosolic phospholipase A2; Cytosolic phospholipase A2; cytosolic phospholipase A2; cPLA2; lysophospholipase; phospholipase A2 group IVA; phosphatidylcholine 2-acylhydrolase; calcium-dependent phospholipid-binding protein; phospholipase A2, group IVA (cytosolic, calcium-dependent); Phospholipase A2 group IVAIncluding the following 2 domains:Phospholipase A2 (EC:3.1.1.4)Alternative name(s):Phosphatidylcholine 2-acylhydrolase], [PLA2G4A; PLA2G4A; PLA2G4; cPLA2-alpha; CPLA2; PLA2G4; cPLA2] |
Gene, Accession # | [c-PLA2], Gene ID: 5321, NCBI: NP_077734.1, UniProt: P47712 |
Catalog # | MBS001555 |
Price | $440, $715 |
Order / More Info | Phospho-c-PLA2 (Ser505) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |