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Antigenic Specificity | USP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect USP1 (a DUB enzyme) in human, mouse and rat samples. Background: Ubiquitinating enzymes (UBEs) catalyze protein ubiquitination, a reversible process countered by deubiquitinating enzymes (DUB) action. There are five DUB subfamilies including the USP, UCH, OTU, MJD, and JAMM enzymes. USP1 belongs to the USP subfamily and is regulated in a cell cycle dependent manner by both transcriptional and ubiquitin-proteosomal mechanisms. USP1 is a nuclear protein and localizes to chromatin where it is specifically associated with FANCD2. USP1 deubiquitinates monoubiquitinated FANCD2, which plays an important role in DNA damage repair and Chk1 protein stability. USP1 deubiquitinates monoubiquitinated PCNA, thereby negativel |
Immunogen | Immunogen: Fusion protein of human USP1. Positive Control: Western Blot: HEK-293 & HeLa cell lysates |
Other Names | [USP1; UBP], [USP1; USP1; UBP; hUBP] |
Gene, Accession # | [USP1], Gene ID: 7398, NCBI: NP_001017415.1, UniProt: O94782 |
Catalog # | MBS840406 |
Price | $385 |
Order / More Info | USP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |