CDIP Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | CDIP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CDIP Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death; loss of its functions contributes to the development of most cancers. CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses. Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway. CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy. Multiple isoforms of CDIP are known to exist. |
| Immunogen | Immunogen: CDIP antibody was raised against a 16 amino acid synthetic peptide near the center of human CDIP. Buffer: CDIP Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [CDIP; I1; CDIP; LITAFL; C16orf5; Cell death-inducing p53-target protein 1; Cell death involved p53-target; chromosome 16 open reading frame 5], [CDIP1; CDIP1; I1; CDIP; LITAFL; C16orf5; C16orf5; CDIP; LITAFL] |
| Gene, Accession # | [C16orf5], Gene ID: 29965, NCBI: NP_037531, UniProt: Q9H305 |
| Catalog # | MBS150664 |
| Price | $375 |
| Order / More Info | CDIP Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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