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Antigenic Specificity | CLCF1 |
Clone | [7E10] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgM,k |
Format | ascites |
Size | 0.2 mL |
Concentration | n/a |
Applications | ELISA (EL/EIA), Western Blot (WB). Other applications not tested. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human CLCF1. This gene is a member of the glycoprotein (gp)130 cytokine family and encodes cardiotrophin-like cytokine factor 1 (CLCF1). CLCF1 forms a heterodimer complex with cytokine receptor-like factor 1 (CRLF1). This dimer competes with ciliary neurotrophic factor (CNTF) for binding to the ciliary neurotrophic factor receptor (CNTFR) complex, and activates the Jak-STAT signaling cascade. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. CLCF1 is a potent neurotrophic factor, B-cell stimulatory agent and neuroendocrine modulator of pituitary corticotroph function. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profus |
Immunogen | Immunogen: Full-length recombinant corresponding to aa29-226 from CLCF1 (AAH12939.1) with GST tag. |
Other Names | CLCF1 (Cardiotrophin-like Cytokine Factor 1, B-cell-stimulating Factor 3, BSF-3, Novel Neurotrophin-1, NNT-1, BSF3, CLC, NNT1) |
Gene, Accession # | Gene ID: 548821, NCBI: BC012939 |
Catalog # | MBS6008087 |
Price | $580 |
Order / More Info | CLCF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |