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Antigenic Specificity | Phospho-Ser1166 NMDA Receptor NR2B Subunit |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Specific for the ~180k NMDAR NR2B subunit phosphorylated at Ser1166. Immunolabeling of the NMDA NR2B subunit band is blocked by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide. Affinity purified rabbit polyclonal antibody |
Immunogen | Antigen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser1166 of the NR2B subunit of the rat NMDA receptor. Immunogen Information: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser1166 conjugated to KLH. Immunogen Species: Rat |
Other Names | [glutamate receptor ionotropic, NMDA 2B; Glutamate receptor ionotropic, NMDA 2B; glutamate receptor ionotropic, NMDA 2B; NR2B; NMDAR2B; glutamate receptor, ionotropic, NMDA2B; N-methyl D-aspartate receptor subtype 2B; glutamate [NMDA] receptor subunit epsilon-2; glutamate receptor, ionotropic, N-methyl D-aspartate 2B; Glutamate [NMDA] receptor subunit epsilon-2; N-methyl D-aspartate receptor subtype 2B], [Grin2b; Grin2b; GluN2B; GluN2B; NMDAR2B; NR2B] |
Gene, Accession # | [GRIN2B], Gene ID: 24410, NCBI: NP_036706.1, UniProt: Q00960 |
Catalog # | MBS502191 |
Price | $360 |
Order / More Info | Phospho-Ser1166 NMDA Receptor NR2B Subunit Antibody from MYBIOSOURCE INC. |
Product Specific References | • Carroll RC, Zukin RS (2002) NMDA-receptor trafficking and targeting: implications for synaptic transmission and plasticity. Trends Neurosci 25:571-577• Clayton DA, Grosshans DR, Browning MD (2002a) Aging and surface expression of hippocampal NMDA receptors. J Biol Chem 277:14367-14369. Clayton DA, Mesches MH, Alvarez E, Bickford PC, Browning MD (2002b) A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat. J Neurosci 22:3628-3637.• Grosshans DR, Clayton DA, Coultrap SJ, Browning MD (2002) LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1. Nat Neurosci 5:27-33.• Wenthold RJ, Prybylowski K, Standley S, Sans N, Petralia RS (2003) Trafficking of NMDA receptors. Annu Rev Pharmacol Toxicol 43:335-358 |