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Antigenic Specificity | beta-Tubulin (Ser-172), phospho-specific |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse, chicken |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA, Western Blot, Immunocytochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody was cross-adsorbed to unphosphorylated bIII-Tubulin (Ser-172) peptide before affinity purification using phosphobIII- Tubulin (Ser-172) peptide (without carrier). The antibody detects a 50 kDa* protein corresponding to the molecular mass of b- Tubulin on SDS-PAGE immunoblots of purified brain tubulin phosphorylated with ERK2 kinase. Microtubules (MTs) are cytoskeletal elements that play an essential role in cell division and cytoplasmic organization. MTs are dynamic polymers of a/b-tubulin heterodimers. At least two populations of MTs, called dynamic and stable according to their rates of turnover, are readily distinguishable in cells. The proteins associated with MTs (MAPs) are among the best-known factors that regulate MT dy |
Immunogen | Immunogen: Phospho-bIII-Tubulin (Ser-172) synthetic peptide (coupled to KLH) corresponding to amino acid residues around serine 172 of human bIII-tubulin. This sequence is identical to similar regions in bI, bII, and bIII-tubulin isotypes, and is well conserved in tubulins from most eukaryotic species. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS472009 |
Price | $385 |
Order / More Info | beta-Tubulin (Ser-172), phospho-specific Antibody from MYBIOSOURCE INC. |
Product Specific References | • Fourest-Lieuvin, A. et al. (2006) Mol. Biol. Cell. 17(3):1041.• Westermann, S. & Weber, K. (2003) Nat. Rev. Mol. Cell. Biol. 4:938.• Fanarraga, M.L. et al. (1999) Eur. J. Neurosci. 11:517.• Diaz-Nido, J. et al. (1990) J Biol. Chem. 265(23):13949. |