Edit |   |
---|---|
Antigenic Specificity | Human CD49d: RPE |
Clone | [Bu49] |
Host Species | Mouse |
Reactive Species | human, dog |
Isotype | IgG1 |
Format | phycoerythrin (RPE) conjugate |
Size | 100 tests |
Concentration | 1.0 mg/ml |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human CD49d monoclonal antibody, clone Bu49 recognizes human CD49d, also known as integrin alpha 4 or VLA-4 alpha subunit. CD49d is a ~150 kDa single pass type I transmembrane glycoprotein. CD49d can be proteolytically cleaved to yield fragments of ~80 and ~70 kDa (Hemler et al. 1987). CD49d associates with either CD29 to form VLA-4 or with Integrin beta-7 to form The Peyer's patches-specific homing receptor LPAM-1, involved in the lymphocyte migration and homing to gut-associated lymphoid tissue (Sackstein 2006) through its interaction with MadCam-1, preferentially expressed on Peyer's patch high endothelial venules and postcapillary venules in lamina propria (Briskin et al. 1997). CD49d is expressed on a broad range of cells in |
Immunogen | Immunogen: Hyatt myeloma cell line. Conjugation: RPE |
Other Names | [CD49d (Bu49); Mouse Human CD49d], [ITGA4; ITGA4; IA4; CD49D; CD49D] |
Gene, Accession # | [CD49d], Gene ID: 3676, NCBI: P13612.3, UniProt: P13612 |
Catalog # | MBS225666 |
Price | $450 |
Order / More Info | Human CD49d: RPE Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |