Human CD49d: RPE Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD49d: RPE
Clone[Bu49]
Host SpeciesMouse
Reactive Specieshuman, dog
IsotypeIgG1
Formatphycoerythrin (RPE) conjugate
Size100 tests
Concentration1.0 mg/ml
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionMouse anti Human CD49d monoclonal antibody, clone Bu49 recognizes human CD49d, also known as integrin alpha 4 or VLA-4 alpha subunit. CD49d is a ~150 kDa single pass type I transmembrane glycoprotein. CD49d can be proteolytically cleaved to yield fragments of ~80 and ~70 kDa (Hemler et al. 1987). CD49d associates with either CD29 to form VLA-4 or with Integrin beta-7 to form The Peyer's patches-specific homing receptor LPAM-1, involved in the lymphocyte migration and homing to gut-associated lymphoid tissue (Sackstein 2006) through its interaction with MadCam-1, preferentially expressed on Peyer's patch high endothelial venules and postcapillary venules in lamina propria (Briskin et al. 1997). CD49d is expressed on a broad range of cells in
ImmunogenImmunogen: Hyatt myeloma cell line. Conjugation: RPE
Other Names[CD49d (Bu49); Mouse Human CD49d], [ITGA4; ITGA4; IA4; CD49D; CD49D]
Gene, Accession #[CD49d], Gene ID: 3676, NCBI: P13612.3, UniProt: P13612
Catalog #MBS225666
Price$450
Order / More InfoHuman CD49d: RPE Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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