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Antigenic Specificity | TLR7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total TLR7 antibody. Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses (1-3). TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-kB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 amino acids known as the TIR domain. Upon activation, TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains including MyD88 (myeloid differentiation factor), MAL/TIRAP (MyD88-adaptor-like/ |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human TLR7. |
Other Names | [TLR7] |
Gene, Accession # | [TLR7], Gene ID: 51284, NCBI: NP_057646.1, UniProt: Q9NYK1 |
Catalog # | MBS9412897 |
Price | $255 |
Order / More Info | TLR7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |