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Antigenic Specificity | VAPB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Vesicle-associated membrane protein-associated protein B/C is a protein that in humans is encoded by the VAPB gene. The VAPB gene is found on the 20th human chromosome. The protein encoded by this gene is a type IV membrane protein found in plasma and intracellular vesicle membranes. The encoded protein is found as a homodimer and as a heterodimer with VAPA. This protein also can interact with VAMP1 and VAMP2 and may be involved in vesicle trafficking.Protein Function: Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation. |
Immunogen | Immunogen: E Coli-derived human VAPB recombinant protein (Position: A2-R55). Subcellular Localization: Endoplasmic reticulum membrane; Present in mitochondria-associated membranes that are endoplasmic reticulum membrane regions closely apposed to the outer mitochondrial membrane. Tissue Specificity: Ubiquitous. Isoform 1 predominates. |
Other Names | [Vesicle-associated membrane protein-associated protein B/C; VAMP-B/VAMP-C; VAMP-associated protein B/C; VAP-B/VAP-C; VAPB; UNQ484/PRO983] |
Gene, Accession # | [VAPB], Gene ID: 9217, NCBI: NP_001182606.1, UniProt: O95292 |
Catalog # | MBS1750630 |
Price | $280 |
Order / More Info | VAPB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |