p53 Tumor Suppressor Protein Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | p53 Tumor Suppressor Protein |
| Clone | [PAb240] |
| Host Species | Mouse |
| Reactive Species | human, monkey, cow, dog, mouse, rat, hamster |
| Isotype | IgG1, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The specificity of this monoclonal antibody to its intended target was tested by HuProtTM Array, containing more than 19,000, full-length human proteins. PAb240 binds to the C-terminus (aa213-217) of both wild type and mutated p53. Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. p53 Binds to a DNA consensus sequence, the p53 response element, and it regulates normal cell growth cycle events by activating transcription of genes, involved either in progression through the cycle, or causing arrest in G1 when the genome is damaged. In most transformed and tumor cells the concentration of p53 is increased 51000 fold over the mi |
| Immunogen | Immunogen: Gel-Purified p53-beta-galactosidase fusion protein containing murine p53 from aa 14-389 |
| Other Names | [Antigen NY-CO-13; BCC7; Cellular Tumor Antigen p53; LFS1; TP53; Transformation Related Protein 53 (TRP53); Tumor Protein p53; Tumor Suppressor p53] |
| Gene, Accession # | [TP53], Gene ID: 7157, NCBI: NP_000537.3, UniProt: P04637 |
| Catalog # | MBS4381303 |
| Price | $190, $340, $340 |
| Order / More Info | p53 Tumor Suppressor Protein Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Bartek et al. 1991. Oncogene. 6(9):1699-703. 2. Gannon et al. 1990. EMBO J. 9(5):1595-602. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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