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Antigenic Specificity | FAK (PTK2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The 21-24 kDa integral proteins, caveolins, are the principal structural components of the cholesterol/sphingolipid-enriched plasma membrane microdomain caveolae. Three members of the caveolin family (caveolin-1,-2, and-3) have been identified with different tissue distributions. Caveolins form hetero-and homooligomers that interact with cholesterol and other lipids (1). Caveolins are involved in diverse biological functions, including vesicular trafficking, cholesterol homeostasis, cell adhesion, and apoptosis, and are also implicated in neurodegenerative disease (2). Caveolins interact with multiple signaling molecules, such as Galpha subunit, tyrosine kinase receptors, PKCs, Src family tyrosine kinases, and eNOS (1, 2). It is believed th |
Immunogen | Immunogen: Fusion protein of human CAV1. Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [CAV1; BSCL3; CAV; CGL3; MSTP085; VIP21], [CAV1; CAV1; CGL3; PPH3; BSCL3; LCCNS; VIP21; MSTP085; CAV] |
Gene, Accession # | [FAK], Gene ID: 857, NCBI: NP_001744.2, UniProt: Q03135 |
Catalog # | MBS859783 |
Price | $290 |
Order / More Info | FAK (PTK2) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Okamoto, T. et al. (1998) J. Biol. Chem. 273, 5419-5422. 2. Smart, E. J. et al. (1999) Mol. Cell. Biol. 19, 7289-7304. 3. Nomura, R. et al. (1999) Mol. Biol. Cell 10, 975-986. 4. Volonte, D. et al. (2001) J. Biol. Chem. 276, 8094-8103. 5. Lee, H. et al. (2000) Mol. Endocrinol. 14, 1750-1775. 6. Schlegel, A. et al. (2001) J. Biol. Chem. 276, 4398-4408. |