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Antigenic Specificity | Rabbit Cortactin (Phospho-Tyr421) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat , human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Cortactin (Tyr421) Ab detects endogenous levels ofCortactin only when phosphorylated at Tyrosine 421. cortactin a cytoskeletal protein that that is involved incoordinating actin reorganization during cell movement.Localizes at the leading edge of lamellipodia during cellmigration. Its amino-terminal acidic domain associates withthe Arp2/3 and WASP complex at F-actin branches. |
Immunogen | Immunogen: A synthesized peptide derived from human Cortactin aroundthe phosphorylation site of Tyrosine 421. Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mMNaCl, 0.02% sodium azide and 50% glycerol. |
Other Names | [src substrate cortactin isoform c; Src substrate cortactin; src substrate cortactin; amplaxin; 1110020L01Rik; oncogene EMS1; ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate); cortactin; Amplaxin; Oncogene EMS1], [CTTN; CTTN; EMS1; EMS1] |
Gene, Accession # | Gene ID: 2017, NCBI: NP_001171669.1, UniProt: Q14247 |
Catalog # | MBS002638 |
Price | $440, $715 |
Order / More Info | Rabbit Cortactin (Phospho-Tyr421) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |