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Antigenic Specificity | Human ICAM-1 |
Clone | [7D22] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: In Western blots, this antibody shows no cross-reactivity with human VECA-2 and human VEGF3, and VCAM1. ICAMs are members of the Ig superfamily of calcium-independent transmembrane glycoproteins. ICAM-1 is a ligand for lymphocyte function-associated (LFA) and Mac-1 integrins and the major human rhinovirus receptor. The primary function of ICAM-1 is to provide adhesion between endothelial cells and leukocytes after stress or injury. The human ICAM-1 gene codes for a 505 amino acid transmembrane glycoprotein containing a 29 amino acid cytoplasmic domain, a 23 amino acid transmembrane domain, and a 453 amino acid extracellular domain. Recombinant human ICAM-1 is a 49.5 kDa glycoprotein comprising the extracellular domain (453 amin |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with human ICAM-1 N-terminal recombinant protein). The IgG1 fraction of culture supernatant was purified by Protein G affinity chromatography. |
Other Names | [human ICAM-1], [ICAM1; ICAM1; BB2; CD54; P3.58; ICAM-1] |
Gene, Accession # | [ICAM-1], Gene ID: 3383, NCBI: NP_000192.2, UniProt: P05362 |
Catalog # | MBS690009 |
Price | $490 |
Order / More Info | Human ICAM-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |