MYT1 (Phospho-Ser83) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMYT1 (Phospho-Ser83)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of MYT1 only when phosphorylated at serine 83. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.Booher R.N., J. Biol. Chem. 272:22300-22306(1997).Liu F., Mol. Cell. Biol. 1
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Serine 83(R-V-S(p)-F-R) derived from Human MYT1.
Other Names[PMYT1; PKMYT1; MYT1 kinase]
Gene, Accession #[MYT1], Gene ID: 9088, NCBI: NP_001245379.1, UniProt: Q99640
Catalog #MBS9402218
Price$200, $255
Order / More InfoMYT1 (Phospho-Ser83) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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