Edit |   |
---|---|
Antigenic Specificity | MYT1 (Phospho-Ser83) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of MYT1 only when phosphorylated at serine 83. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.Booher R.N., J. Biol. Chem. 272:22300-22306(1997).Liu F., Mol. Cell. Biol. 1 |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Serine 83(R-V-S(p)-F-R) derived from Human MYT1. |
Other Names | [PMYT1; PKMYT1; MYT1 kinase] |
Gene, Accession # | [MYT1], Gene ID: 9088, NCBI: NP_001245379.1, UniProt: Q99640 |
Catalog # | MBS9402218 |
Price | $200, $255 |
Order / More Info | MYT1 (Phospho-Ser83) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |