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Antigenic Specificity | BCL10 (N-term), 24-51 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This BCL10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-51 amino acids from the N-terminal region of human BCL10. This gene was identified by its translocation in a case ofmucosa-associated lymphoid tissue (MALT) lymphoma. The proteinencoded by this gene contains a caspase recruitment domain (CARD),and has been shown to induce apoptosis and to activate NF-kappaB.This protein is reported to interact with other CARD domaincontaining proteins including CARD9, 10, 11 and 14, which arethought to function as upstream regulators in NF-kappaB signaling.This protein is found to form a complex with MALT1, a proteinencoded by another gene known to be translocated in MAL |
Immunogen | n/a |
Other Names | [B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; c-E10; Mammalian CARD-containing adapter molecule E10; mE10; BCL10; CIPER; CLAP] |
Gene, Accession # | [BCL10], Gene ID: 8915, NCBI: NP_003912.1, UniProt: O95999 |
Catalog # | MBS9205918 |
Price | $165, $370 |
Order / More Info | BCL10 (N-term), 24-51 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bhattacharyya, S., et al. Exp. Cell Res. 316(19):3317-3327(2010) Edin, S., et al. Mol. Immunol. 47 (11-12), 2057-2064 (2010) : Davila, S., et al. Genes Immun. 11(3):232-238(2010) Bhattacharyya, S., et al. J. Biol. Chem. 285(1):522-530(2010) Rehman, A.O., et al. Int J Oral Sci 1(3):105-118(2009) |