CAMK Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | CAMK |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CaMKII is an important member of the calcium/calmodulin-activated protein kinase family, functioning in neural synaptic stimulation and T cell receptor signaling (1, 2). CaMKII has catalytic and regulatory domains. Ca2+/calmodulin binding to the CaMKII regulatory domain relieves autoinhibition and activates the kinase (3). The activated CaMKII further autophosphorylates at Thr286 to render the kinase constitutively active (3). The threonine phosphorylation state of CaMKII can be regulated through PP1/PKA. PP1 (protein phosphatase 1) dephosphorylates phospho-CaMKII at Thr286. PKA (protein kinase A) prevents phospho-CaMKII (Thr286) dephosphorylation through an inhibitory effect on PP1 (4). |
| Immunogen | Immunogen: Recombinant protein of human CAMK2G Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [CAMK; CAMK-II; CAMKG; FLJ16043; MGC26678] |
| Gene, Accession # | [CAMK], Gene ID: 818, NCBI: NP_001191421.1, UniProt: Q13555 |
| Catalog # | MBS8505211 |
| Price | $310 |
| Order / More Info | CAMK Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Hughes, K. et al. (2001) J. Biol. Chem. 276, 36008-36013. 2. Barria, A. et al. (1997) Science 276, 2042-2045. 3. Barkai, U. et al. (2000) Mol. Endocrinol. 14, 554-563. 4. Makhinson, M. et al. (1999) J. Neurosci. 19, 2500-2510. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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