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Antigenic Specificity | PHC3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PHC3 antibody is human, mouse and rat specific. At least six isoforms of PHC3 are known to exist. Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes throughout development (1). PHC3 (Polyhomeotic-like protein 3), also known as Early development regulatory protein 3, is a 983 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex (2). PRC1 complex acts via chromatin remodeling and modification of histones. PHC3 contains 1 FCS-type zinc finger and SAM (sterile alpha motif) domain (2-3). PHC 3 has been regarded as a candidate tumor suppressor of osteosarcoma (4). |
Immunogen | Immunogen: PHC3 antibody was raised against a 19 amino acid peptide near the amino terminus of human PHC3. Buffer: PHC3 antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [PHC3; EDR3; HPH3; EDR3; PH3; Polyhomeotic-like protein 3; Early development regulatory protein 3; hPH3; polyhomeotic homolog 3 (Drosophila)], [PHC3; PHC3; EDR3; HPH3; EDR3; PH3; hPH3] |
Gene, Accession # | [PHC3], Gene ID: 80012, NCBI: NP_079223, UniProt: Q8NDX5 |
Catalog # | MBS153385 |
Price | $375 |
Order / More Info | PHC3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |