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Antigenic Specificity | C/EBP-Beta |
Clone | [47A1] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 k |
Format | Protein G purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CCAAT/enhancer-binding proteins (C/EBPs) are a family of basic leucine zipper (bZIP) DNA binding proteins that play important roles in normal cellular differentiation and function in a variety of tissues. The C/EBP family is critical for innate immunity and inflammatory response, and consists of five core members: C/EBPalpha, C/EBPbeta, C/EBPdelta, C/EBPepsilon, and C/EBPgamma. Among these proteins, C/EBPbeta is usually highly expressed in liver, intestine, lung and adipose. C/EBPbeta has three isoforms, two activator, (LAP* and LAP) and a repressor (LIP). These isoforms are differentially translated from the same mRNA. The expression of these isoforms is developmentally and hormonally regulated. |
Immunogen | Immunogen: Recombinant human C/EBP-beta (1-271 aa) purified from E. coli |
Other Names | [CEBPB (CCAAT/enhancer binding protein; beta); LAP; CRP2; TCF5; IL6DBP; NF-IL6; MGC32080,C/EBP-beta; CCAAT/enhancer binding protein (C/EBP) beta; NFIL6; liver-enriched transcriptional activator protein; nuclear factor of interleukin 6; interleukin 6-dependent DNA-binding protein;], [CEBPB; CEBPB; TCF5; IL6DBP; NF-IL6; C/EBP-beta; TCF-5] |
Gene, Accession # | [C/EBP-Beta], Gene ID: 1051, NCBI: NP_005185, UniProt: P17676 |
Catalog # | MBS200024 |
Price | $240, $315 |
Order / More Info | C/EBP-Beta Antibody from MYBIOSOURCE INC. |
Product Specific References | Lekstrom-Himes J. et al. (1998) J Biol. Chem. 273, 28545-28548; Parkin SE. et al. (2002) J Biol. Chem.; 277, 23563-23572; Su WC. et al. (2003) J Biol. Chem. 278, 51150-51158 |