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Antigenic Specificity | RAN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, monkey |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), RIP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ran is a small GTPase of the Ras family that plays a central role in the spacial and temperal organization of eukaryotic cells. During interphase, Ran-GDP localizes to the cytoplasm and Ran-GTP to the nucleus. This polarized localization of Ran ensures its role in nuclear transport (1). During mitosis, Ran-GTP is chromatin associated, where it promotes spindle assembly and nuclear envolope formation (1,2). In S phase, Ran-GTP associates with and inhibits MCM helicase, ensuring precise chromosomal DNA duplication during the cell cycle (3) |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [RAN; ARA24; Gsp1; TC4], [RAN; RAN; TC4; Gsp1; ARA24; ARA24] |
Gene, Accession # | [RAN], Gene ID: 5901, NCBI: P62826.3, UniProt: P62826 |
Catalog # | MBS127169 |
Price | $200, $275, $430 |
Order / More Info | RAN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |