GSK-3alpha Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGSK-3alpha
Clonepolyclonal
Host SpeciesMouse
Reactive Speciesn/a
Isotypen/a
Formatperoxidase (HRP) conjugate
Size1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunoprecipitation (IP)
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DescriptionSpecificity: Human/Mouse GSK-3alpha. Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3alpha and GSK-3beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics, and cell motility.
ImmunogenImmunogen: Recombinant N-terminal GSK-3alpha. Conjugation: HRP (Horseradish Peroxidase)
Other Namesn/a
Gene, Accession #[GSK-3alpha]
Catalog #MBS679337
Price$435
Order / More InfoGSK-3alpha Antibody from MYBIOSOURCE INC.
Product Specific References1. Meares GP, Zmijewska AA, Jope RS. HSP105 interacts with GRP78 and GSK3 and promotes ER stress-induced caspase-3 activation. Cell Signal. 2008;20:347-58. (IP)2. Sun M, Song L, Li Y, Zhou T, Jope RS. Identification of an antiapoptotic protein complex at death receptors. Cell Death Differ. 2008;15:1887-1900. (IP)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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