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Antigenic Specificity | NDRG1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | N-myc downstream-regulated gene 1 (NDRG1), also termed Cap43, Drg1, RTP/rit42, and Proxy-1, is a member of the NDRG family, which is composed of four members (NDRG1-4) that function in growth, differentiation, and cell survival (1-5). NDRG1 is ubiquitously expressed and highly responsive to a variety of stress signals including DNA damage (4), hypoxia (5), and elevated levels of nickel and calcium (2). Expression of NDRG1 is elevated in N-myc defective mice and is negatively regulated by N- and c-myc (1, 6). During DNA damage, NDRG1 is induced in a p53-dependent fashion and is necessary for p53-mediated apoptosis (4, 7). Research studies have shown that NDRG1 may also play a role in cancer progression by promoting differentiation, inhibitin |
Immunogen | Immunogen: Recombinant protein of human NDRG1 Observed Molecular Weight: 43kDa |
Other Names | [CAP43; CMT4D; DRG1; GC4; HMSNL; NDR1; NMSL; PROXY1; RIT42; RTP; TARG1; TDD5] |
Gene, Accession # | [NDRG1], Gene ID: 10397, NCBI: CAG33123.1, UniProt: Q92597 |
Catalog # | MBS2519964 |
Price | $150, $225, $360 |
Order / More Info | NDRG1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |