Edit |   |
---|---|
Antigenic Specificity | Human ADAM-9 |
Clone | [8A15] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ADAM9, also known as MDC9 or meltrin gamma, is a member of the ADAM family that contains a disintegrin and metalloprotease-like domain. Like other membrane-anchored ADAMs, ADAM9 consists of a pro domain with a cysteine switch and furin cleavage sequence, a catalytic domain with the zinc-binding site and Metturn expected for reprolysins, a disintegrin-like domain, a cysteinerich domain, an EGF-like domain, a transmembrane domain, and the cytoplasmic domain. ADAM9 is able to cleave peptides corresponding to cleavage sites of tumor necrosis factor-alpha (TNFalpha), the p75 TNF receptor, the betaamyloid protein precursor, and the c-kit ligand 1, implying that it may participate in shedding of these membrane proteins. In fact, ADAM9 has been sho |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse)immunized with Human ADAM-9 (extracellular domain) recombinant protein. |
Other Names | [ADAM9; MCMP; MDC9; CORD9; Mltng], [ADAM9; ADAM9; MCMP; MDC9; CORD9; Mltng; KIAA0021; MCMP; MDC9; MLTNG; ADAM 9] |
Gene, Accession # | [ADAM-9], Gene ID: 8754, NCBI: NP_003807.1, UniProt: Q13443 |
Catalog # | MBS690700 |
Price | $475 |
Order / More Info | Human ADAM-9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |