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Antigenic Specificity | ARHE (Center), 133-165 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: porcine, rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ARHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-165 amino acids from the Central region of human ARHE. Members of the Rho family of Ras-related GTPases, such as ARHE, regulate the organization of the actin cytoskeleton in response to extracellular growth factors. Like Ras (MIM 190020), Rho family members appear to cycle between an inactive GDP-bound form and an active GTP-bound form. Three major regulators of Rho activity have been identified: RhoGDIs, which interact with the GDP-bound Rho proteins to keep them in a resting complex (see MIM 601925); GEFs, which promote GDP/GTP exchange leading to activation of Rho proteins (see MIM 601855); and GAPs, which stimulate GTP hydrolysis a |
Immunogen | n/a |
Other Names | [Rho-related GTP-binding protein RhoE; Protein MemB; Rho family GTPase 3; Rho-related GTP-binding protein Rho8; Rnd3; RND3; ARHE; RHO8; RHOE] |
Gene, Accession # | [RND3], Gene ID: 390, NCBI: NP_001241667.1, UniProt: P61587 |
Catalog # | MBS9209800 |
Price | $165, $370 |
Order / More Info | ARHE (Center), 133-165 Antibody from MYBIOSOURCE INC. |
Product Specific References | Pinner,S., Nat. Cell Biol. 10 (2), 127-137 (2008) Poch,E., Exp. Cell Res. 313 (4), 719-731 (2007) Ongusaha,P.P., Curr. Biol. 16 (24), 2466-2472 (2006) |