SKI Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySKI
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mousepredicted: bovine, horse, dog, chicken, Xenopus
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Peptide ELISA (EIA)
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DescriptionSpecificity: SKI Antibody detects endogenous levels of SKI. Description: May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling.Post Translational Modifications: Ubiquitinated by RNF165, promoting proteasomal degradation, leading to enhance the BMP-Smad signaling.Subunit Structure: Interacts with SMAD2, SMAD3 and SMAD4. Interacts with HIPK2. Part of a complex with HIPK2 and SMAD1/2/3. Interacts with PRDM16 and SMAD3; the interaction with PRDM16 promotes the recruitment SMAD3-HDAC1 complex on the promoter of TGF-beta target genes.Similarity: Belongs to the SKI family.
ImmunogenImmunogen: A synthesized peptide derived from human SKI.
Other Names[Avian sarcoma viral (v ski) oncogene homolog; C oncogene; C ski; Proto-oncogene c-Ski; SKI; Ski oncogene; Ski oncoprotein; SKI_HUMAN; SKV; v ski avian sarcoma viral oncogene homolog; v ski sarcoma viral oncogene homolog]
Gene, Accession #[SKI], Gene ID: 6497, NCBI: P12755.1, UniProt: P12755
Catalog #MBS9610824
Price$225, $280, $340
Order / More InfoSKI Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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