Zap70 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Zap70 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Zap70 |
| Clone | [1484CT290.68.62] |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG2a,k |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Zap70 antibody is generated from a mouse immunized with a recombinant protein. Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Regulates motility, adhesion and cytokine expression of mature T-cells, as well as thymocyte development. Contributes also to the development and activation of primary B-lymphocytes. When antigen presenting cells (APC) activate T-cell receptor (TCR), a serie of phosphorylations lead to the recruitment of ZAP70 to the doubly phosphorylated TCR component CD3Z through ITAM motif at the plasma membrane. This recruitment serves to localization to the stimulated TCR and to relieve its autoinhibited conformation. Release of ZAP70 active conformation is further stabilized by |
| Immunogen | n/a |
| Other Names | [Tyrosine-protein kinase ZAP-70; 70 kDa zeta-chain associated protein; Syk-related tyrosine kinase; Zap70; Srk; Zap-70] |
| Gene, Accession # | [Zap70], Gene ID: 22637, NCBI: NP_001276541.1, UniProt: P43404 |
| Catalog # | MBS9200657 |
| Price | $165, $370 |
| Order / More Info | Zap70 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Gauen L.K.T.,et al.Mol. Cell. Biol. 14:3729-3741(1994). Wiest D.L.,et al.Immunity 6:663-671(1997). Kuroyama H.,et al.Biochem. Biophys. Res. Commun. 315:935-941(2004). Ikeda T.,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. Carninci P.,et al.Science 309:1559-1563(2005). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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