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Antigenic Specificity | Human CD284 |
Clone | [HTA125] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2a |
Format | biotin conjugate |
Size | 0.1 mg |
Concentration | IgG concentration 0.1 mg/ml |
Applications | Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human CD284 antibody, clone HTA125 recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. This antibody has been demonstrated to block activation of monocytes with LPS. MyBioSource recommend the use of MBS211211 for this purpose. |
Immunogen | Immunogen: Ba/F3 cell line expressing TLR4 (CD284). Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | [toll-like receptor 4 isoform C; Toll-like receptor 4; toll-like receptor 4; hToll; homolog of Drosophila toll; toll-like receptor 4; hToll; CD_antigen: CD284], [TLR4; TLR4; TOLL; CD284; TLR-4; ARMD10] |
Gene, Accession # | [CD284], Gene ID: 7099, NCBI: NP_003257.1, UniProt: O00206 |
Catalog # | MBS210389 |
Price | $370 |
Order / More Info | Human CD284 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |