Human CD284 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD284
Clone[HTA125]
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG2a
Formatbiotin conjugate
Size0.1 mg
ConcentrationIgG concentration 0.1 mg/ml
ApplicationsFlow cytometry (FC/FACS)
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DescriptionMouse anti Human CD284 antibody, clone HTA125 recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. This antibody has been demonstrated to block activation of monocytes with LPS. MyBioSource recommend the use of MBS211211 for this purpose.
ImmunogenImmunogen: Ba/F3 cell line expressing TLR4 (CD284). Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human
Other Names[toll-like receptor 4 isoform C; Toll-like receptor 4; toll-like receptor 4; hToll; homolog of Drosophila toll; toll-like receptor 4; hToll; CD_antigen: CD284], [TLR4; TLR4; TOLL; CD284; TLR-4; ARMD10]
Gene, Accession #[CD284], Gene ID: 7099, NCBI: NP_003257.1, UniProt: O00206
Catalog #MBS210389
Price$370
Order / More InfoHuman CD284 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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