Tyrosinase (Melanoma Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Tyrosinase (Melanoma Marker) |
| Clone | [TYR/2024R] |
| Host Species | Rabbit |
| Reactive Species | human. |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a cluster of proteins between 70-80kDa, identified as tyrosinase. Occasionally a minor band at 55kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3, 4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful |
| Immunogen | Immunogen: Recombinant tyrosinase protein Cellular Localization: Cytoplasmic |
| Other Names | [ATN; CMM8; LB24-AB; Monophenol monooxygenase; OCA1; OCA1A; Oculocutaneous albinism IA; SHEP3; SK29-AB; Tumor rejection antigen AB; TYR] |
| Gene, Accession # | [TYR], Gene ID: 7299, NCBI: NP_000363.1, UniProt: P14679 |
| Catalog # | MBS4380273 |
| Price | $190, $340, $340 |
| Order / More Info | Tyrosinase (Melanoma Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Chen Y-T, et. al. Proc. Natl. Acad. Sci. USA, 1995, 92:8125-8129. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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