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Antigenic Specificity | CD7 (T-Cell Leukemia Marker) |
Clone | [CD7/3737] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of 40kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 ass |
Immunogen | Immunogen: Recombinant human full-length CD7 protein |
Other Names | [GP40; Leu9; p41; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41] |
Gene, Accession # | [CD7], Gene ID: 924, NCBI: NP_006128.1, UniProt: P09564 |
Catalog # | MBS4381398 |
Price | $190, $340, $340 |
Order / More Info | CD7 (T-Cell Leukemia Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Saxena A, et al. Biologic and clinical significance of CD7 expression in acute myeloid leukemia. Am J Hematol. 1998;58(4):278-84. |