Edit |   |
---|---|
Antigenic Specificity | Prion protein PrP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Major prion protein(PRNP) detection. Tested with WB, IHC-P in Mouse, Rat. Background: PRNP(prion protein), also known as CD230 and PRP, is a protein that in humans is encoded by the PRNP gene. The major prion protein is expressed in the brain and several other tissues. Expression is most predominant in the nervous system but occurs in many other tissues throughout the body. Puckett et al.(1991)identified a RFLP with a high degree of heterozygosity in the 5-prime region of the PRNP gene, which might serve as a useful marker for the pter-p12 region of chromosome 20. PRNP is associated with a variety of cognitive deficiencies and neurodegenerative diseases such as Creutzfeldt-Jakob disease, bovin |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse Prion protein PrP (143-159aa DWEDRYYRENMYRYPNQ), identical to the related rat sequence. |
Other Names | [Major prion protein(PrP); prion protein; Alternative prion protein; major prion protein; AltPrP; ASCR; atal familial insomnia; CD230; CD230 antigen; CJD; Creutzfeld Jakob disease; Creutzfeld Jakob Disease Gerstmann Strausler Scheinker Syndrome Fatal Familial Insomnia; Gerstmann-Strausler-Scheinker syndrome; GSS; KURU; Major prion protein; MGC26679; p27 30; PRIO_HUMAN; Prion protein; Prion related protein; PRIP; Prni; Prnp; PrP 27-30; PrP; PrP27 30; PrP27-30; PrP33 35C; PrP33-35C; PrPC; PrPSc; Sinc], [Prnp; Prnp; PrP; PrPC; Sinc; CD230; PrPSc; Prn-i; Prn-p; PrP<C>; AA960666; AI325101; prP27-30; prP33-35C; Prn-p; Prp; PrP] |
Gene, Accession # | [PRNP], Gene ID: 19122, NCBI: P04925.2, UniProt: P04925 |
Catalog # | MBS175399 |
Price | $315 |
Order / More Info | Prion protein PrP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |