TYRO3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTYRO3
Clone[64CT15.6.2.3.1]
Host SpeciesMouse
Reactive Specieshuman
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThis TYRO3 Monoclonal antibody is generated from mouse immunized with human recombinant TYRO3 protein. The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses.
Immunogenn/a
Other Names[Tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase BYK; Tyrosine-protein kinase DTK; Tyrosine-protein kinase RSE; Tyrosine-protein kinase SKY; Tyrosine-protein kinase TIF; TYRO3; BYK; DTK; RSE; SKY; TIF]
Gene, Accession #[TYRO3], Gene ID: 7301, NCBI: NP_006284.2, UniProt: Q06418
Catalog #MBS9200037
Price$165, $370
Order / More InfoTYRO3 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesAssociation study between polymorphims in GAS6-TAM genes and carotid atherosclerosis. Hurtado B, et al. Thromb Haemost, 2010 Sep. PMID 20664904. Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor. Zhu D, et al. Blood, 2010 Jun 10. PMID 20348395. A genomic screen identifies TYRO3 as a MITF regulator in melanoma. Zhu S, et al. Proc Natl Acad Sci U S A, 2009 Oct 6. PMID 19805117. TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer. Linger RM, et al. Adv Cancer Res, 2008. PMID 18620092. Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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