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Antigenic Specificity | TYRO3 |
Clone | [64CT15.6.2.3.1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TYRO3 Monoclonal antibody is generated from mouse immunized with human recombinant TYRO3 protein. The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. |
Immunogen | n/a |
Other Names | [Tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase BYK; Tyrosine-protein kinase DTK; Tyrosine-protein kinase RSE; Tyrosine-protein kinase SKY; Tyrosine-protein kinase TIF; TYRO3; BYK; DTK; RSE; SKY; TIF] |
Gene, Accession # | [TYRO3], Gene ID: 7301, NCBI: NP_006284.2, UniProt: Q06418 |
Catalog # | MBS9200037 |
Price | $165, $370 |
Order / More Info | TYRO3 Antibody from MYBIOSOURCE INC. |
Product Specific References | Association study between polymorphims in GAS6-TAM genes and carotid atherosclerosis. Hurtado B, et al. Thromb Haemost, 2010 Sep. PMID 20664904. Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor. Zhu D, et al. Blood, 2010 Jun 10. PMID 20348395. A genomic screen identifies TYRO3 as a MITF regulator in melanoma. Zhu S, et al. Proc Natl Acad Sci U S A, 2009 Oct 6. PMID 19805117. TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer. Linger RM, et al. Adv Cancer Res, 2008. PMID 18620092. Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348. |